Services

Regulatory Affairs for Medical Devices (EU MDR/IVDR & US FDA)

Move from uncertainty to approval with a submission-first plan. We help teams define claims, select the right pathways, build audit-ready documentation, and communicate effectively with Notified Bodies and FDA—covering Medical Devices including SaMD.

MDR / IVDRFDA QMSRClassification ISO 13485ISO 14971DHF & Technical Documentation 510(k) / De NovoNotified Body / FDA comms

EU & US coverage • Calm audits • Reviewer-ready files

Medical Device Regulatory Services

Regulatory strategy

Intended use/indications, target markets, and route to market. Clear acceptance criteria and timelines.

  • Labeling & claims alignment
  • Market sequencing plan (EU/US)
  • Submission roadmap

Classification assessment

EU MDR/IVDR classification and US FDA class/product codes based on risk, claims, and technology.

  • EU classification memo
  • FDA regulation & product code mapping
  • Predicate analysis (if applicable)

Gap analysis

Compare current QMS & evidence to MDR Annex II/III and/or FDA submission expectations.

  • ISO 13485 alignment
  • Risk (ISO 14971) integration
  • PMS/PMCF & vigilance fit

Risk & safety

Hazard analysis, benefit-risk, usability and cybersecurity woven into claims and documentation.

  • ISO 14971 risk file
  • IEC 62366-1 usability evidence
  • IEC 81001-5-1 cybersecurity plan

DHF & Technical Documentation

Right-sized files mapped to reviewer checkpoints (SaMD & hardware).

  • Design history & traceability
  • GSPR & essential performance
  • Labeling/UDI & UIM

Submissions & agency comms

Prepare, submit, and respond—efficiently and on time.

  • NB Q&A & CAPA alignment
  • FDA 510(k)/De Novo content
  • Deficiency responses

Clinical operations/PMCF and eQMS platform work are coordinated with vetted partners when needed.

EU MDR/IVDR pathway

What we handle

  • Classification & conformity assessment route
  • Technical Documentation (Annex II/III)
  • GSPR matrix & evidence mapping
  • Clinical evaluation & PMCF framework coordinated
  • PMS plan, vigilance & trend reporting
  • UDI/EUDAMED readiness
  • NB selection, submissions, and responses

SaMD specifics

  • Software safety classification & SOUP control
  • IEC 62304 documentation set
  • Human factors & cybersecurity annexes

We align software life-cycle evidence with claims and risk to avoid “nice-to-have” artifacts.

US FDA pathway

What we handle

  • QMSR-aligned QMS & documentation
  • Regulation & product code mapping
  • Submission type selection (510(k) / De Novo)
  • 510(k) content build & RTA readiness
  • U.S. labeling & UDI/GUDID coordination
  • Pre-Sub & deficiency responses

SaMD specifics

  • Software documentation (architecture, risk, verification)
  • Clinical & performance summaries (as applicable)
  • Cybersecurity documentation aligned to FDA expectations

What you’ll receive

DeliverablePurposeTypical outputs
Regulatory strategy & planDefine route to market, timelines, ownersClaims map, pathway decision, submission schedule
Classification memoDocument EU/FDA class & rationaleEU rules & FDA product codes with justification
Gap analysisIdentify remediation to meet MDR/IVDR or FDAAnnex II/III & 510(k) checklists, prioritized actions
Risk & safety packageDemonstrate risk control & usabilityISO 14971 file, IEC 62366-1, cybersecurity plan
SaMD dossier (if applicable)Software life-cycle evidenceIEC 62304 docs, SOUP list, verification reports
Technical Documentation / 510(k)Submission-ready filesTD index or 510(k) sections with cross-references
Agency interaction logTrack questions & responsesNB/FDA correspondence & commitments register

Clinical/PMCF execution and eQMS implementation delivered with partners when required.

How we work

1Discover. Device, claims, class, markets, gaps.
2Plan. Submission roadmap with owners, deliverables, dates.
3Build. Evidence packs; align QMS; coordinate partners.
4Review. Reviewer-style critique & remediation loop.
5Submit & support. NB/FDA comms, responses, and handover.

PRRC & US Agent (optional add-ons)

PRRC (EU)

Eligible micro/small enterprises can appoint CENIT as the named PRRC with EU presence and defined availability.

US FDA Agent

Foreign establishments can designate CENIT as U.S. Agent to handle FDA communications and inspection scheduling.

We ensure seamless integration of these roles with your submission plan and QMS.

Regulatory Affairs FAQs

Do you support both SaMD and hardware devices?

Yes. We regularly handle standalone software, connected systems, and traditional devices, aligning evidence to claims and risk.

What if we already have a QMS?

Great—we’ll map it to MDR/IVDR or QMSR, identify only the gaps, and keep changes lean.

Can you work with our clinical/eQMS vendors?

Yes. We coordinate with your preferred partners or bring vetted partners for PMCF, clinical ops, and eQMS.

How quickly can we start?

Discovery can begin within days. After a short scoping call, we provide a dated plan with owners and deliverables.

Will you sign an NDA?

Yes. We treat shared information as confidential and can use your NDA template or ours.

Ready to accelerate your submission?

Book a free consultation. We’ll confirm class, outline your pathway, and share a practical deliverables plan.

Book a Free Consultation

Contact us to find out more about Regulatory Affairs